I think a better question would be to know if the style you wanna bring to your webcomic will help the story and the mood of your comic . Trying to do as much as you can on purpose is really important . Most of the time the " general rule " says that thick lines better represent static stuff, while thin or blurry lines is more about movement. in some comics, where dialogs are important, and character are most of the time standing in a static pose, use of heavy lines is quite nice, but then, dunno what your webcomic is about ! maybe try a few pages this way and drop them here to get some critics ?